Description

This dataset involves 228 individuals with expression data for all four conditions/contexts, that is, in the naive state (CD14), after 2-hour LPS (LPS2), after 24-hour LPS (LPS24), and after exposure to IFN (IFN). Also included are the probe information and the demographics information about individuals. For genotype data for these individuals, please refer to JKscience_genotype.

Usage

JKscience_expression <- dRDataLoader(RData.customised = "JKscience_expression")

Value

a list with 3 components:

• eContext: a list of 4 components, each for one of four conditions/contexts (that is, "CD14", "LPS2", "LPS24" and "IFN") and each containing a matrix of probes X individuals
• probeInfo: a list of 2 components, both storing probe information including their genomic locations. The component JKscience_expression$probeInfo$Info contains a data frame, the second JKscience_expression$probeInfo$GR is an object of class "GRanges"
• demoInfo: a data frame containing demographics information about individuals

References

Fairfax et al. (2014). Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression. Science, 343(6175):1246949.

Examples

JKscience_expression <- dRDataLoader(RData.customised='JKscience_expression')

Error in dRDataLoader(RData.customised = "JKscience_expression"): unused argument (RData.customised = "JKscience_expression")
names(JKscience_expression)

Error in eval(expr, envir, enclos): object 'JKscience_expression' not found
# for eContext
str(JKscience_expression$eContext)

Error in str(JKscience_expression$eContext): object 'JKscience_expression' not found
dim(JKscience_expression$eContext$CD14)

Error in eval(expr, envir, enclos): object 'JKscience_expression' not found
JKscience_expression$eContext$CD14[1:5, 1:5]

Error in eval(expr, envir, enclos): object 'JKscience_expression' not found
# for probeInfo
names(JKscience_expression$probeInfo)

Error in eval(expr, envir, enclos): object 'JKscience_expression' not found
JKscience_expression$probeInfo$Info[1:5, ]

Error in eval(expr, envir, enclos): object 'JKscience_expression' not found
JKscience_expression$probeInfo$GR

Error in eval(expr, envir, enclos): object 'JKscience_expression' not found
# for demoInfo
JKscience_expression$demoInfo[1:5, ]

Error in eval(expr, envir, enclos): object 'JKscience_expression' not found